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DABCYL-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-EDANS

CAS No.: 1802078-36-9

DABCYL-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-EDANS also called DABCYL-(Asn670,Leu671)-APP770 (667
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CAS 1802078-36-9
Sequence DABCYL-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-EDANS
Sequence Single DABCYL-SEVNLDAF-EDANS
Molecular Formula C71H91N15O21S
Molecular Weight 1522.66
Synonyms DABCYL-(Asn670,Leu671)-APP770 (667-675)-EDANS
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Alzheimer’s Disease
Description DABCYL-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-EDANS also called DABCYL-(Asn670,Leu671)-APP770 (667-675)-EDANS, is a FRET substrate for β-Secretase corresponding to residues 667 to 674, SEVNLDAEF, of the Swedish double mutation (K670N/M671L) of APP. The sequence can also be cleaved by cathepsin D.