CAS | 1802078-36-9 |
Sequence | DABCYL-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-EDANS |
Sequence Single | DABCYL-SEVNLDAF-EDANS |
Molecular Formula | C71H91N15O21S |
Molecular Weight | 1522.66 |
Synonyms | DABCYL-(Asn670,Leu671)-APP770 (667-675)-EDANS |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Alzheimer’s Disease |
Description | DABCYL-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-EDANS also called DABCYL-(Asn670,Leu671)-APP770 (667-675)-EDANS, is a FRET substrate for β-Secretase corresponding to residues 667 to 674, SEVNLDAEF, of the Swedish double mutation (K670N/M671L) of APP. The sequence can also be cleaved by cathepsin D. |