PeptideDB

(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)

CAS No.: 150234-52-9

(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675) also called (Asn670,Leu671)-APP770 (667-675), APP770 (667-6
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CAS 150234-52-9
Sequence H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-OH
Sequence Single SEVNLDAEF
Molecular Formula C44H66N10O18
Molecular Weight 1023.07
Synonyms (Asn670,Leu671)-APP770 (667-675), APP770 (667-675) Swedish Mutation, (Asn670, Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Alzheimer’s Disease
Description (Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675) also called (Asn670,Leu671)-APP770 (667-675), APP770 (667-675) Swedish Mutation, (Asn670, Leu671)-Amyloid β/A4 Protein Precursor770 (667-675), corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer’s disease, therefore referred to as the ‘Swedish’ mutation (K670N/M671L). The peptide has been used for assaying cleavage at leucine-aspartate by cathepsin G and chymotrypsin, whereas neither cathepsin B, D nor L generated any products.