CAS | 114056-26-7 |
Sequence | β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-Tyr-NH2 (Disulfide bond) |
Sequence Single | β-Mercapto-β,β-cyclopentamethylene-propionyl-Y(Me)-ITNCP-Orn-Y-NH2(Disulfide bond) |
Molecular Formula | C54H79N11O13S2 |
Molecular Weight | 1154.42 |
Synonyms | OVTA, Vasotocin analog |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Pituitary & Hypothalamic Hormones |
Description | (d(CH2)5¹,Tyr(Me)2,Thr4,Orn8,Tyr-NH2⁹)-Vasotocin also called OVTA, Vasotocin analog, is a oxytocin antagonist, it shows enhanced affinity for rat uterine oxytocin receptors after iodination. |
References | 1. Muramylpeptides and lipopeptides: Studies towards immunostimulants. G.Baschang, Tetrahedron, 45, 6331 (1989) 2. Up-regulation of mesotocin receptors in the tammar wallaby myometrium is pregnancy-specific and independent of estrogen. A.L.Siebel et al., Biol. Reprod., 66, 1237 (2002) 3. 125I-labelled d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH2(9)]OVT: a selective oxytocin receptor ligand. J.Elands et al., Eur. J. Pharmacol., 147, 197 (1988) |