| CAS | 115499-13-3 |
| Sequence | β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-OH (Disulfide bond) |
| Sequence Single | β-Mercapto-β,β-cyclopentamethylene-propionyl-Y(Me)-ITNCP-Orn-OH(Disulfide bond) |
| Molecular Formula | C45H69N9O12S2 |
| Molecular Weight | 992.23 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Pituitary & Hypothalamic Hormones |
| Description | (d(CH2)5¹,Tyr(Me)2,Thr4,Orn8,des-Gly-NH2⁹)-Vasotocin is a potent and selective in vivo oxytocin antagonist. |
| References | 1. Involvement of arginine vasotocin in reproductive events in the male newt Cynops pyrrhogaster. F.Toyoda et al., Horm. Behav., 44, 346 (2003) 2. Design and synthesis of highly selective in vitro and in vivo uterine receptor antagonists of oxytocin: comparisons with Atosiban. M.Manning et al., Int. J. Pept. Protein Res., 46, 244 (1995) 3. Modulation of oxytocin and vasopressin release from rat neurosecretosomes: the roles of VIP oxytocin and GABA. N.Falke, Neuropeptides, 18, 143 (1991) |
(d(CH2)5¹,Tyr(Me)2,Thr4,Orn8,des-Gly-NH2⁹)-Vasotocin
CAS No.: 115499-13-3
(d(CH2)5¹,Tyr(Me)2,Thr4,Orn8,des-Gly-NH2⁹)-Vasotocin is a potent and selective in vivo oxytocin antagonist.
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