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Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu)

CAS No.: 158778-21-3

Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu) corresponds to the autophosphorylation segment around Tyr751 of the PDGF receptor
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CAS 158778-21-3
Sequence Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu)
Sequence Single Cyclo(-G(p)YVPML)
Molecular Formula C32H49N6O10PS
Molecular Weight 740.82
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Protein-Tyrosine Kinases
Description Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu) corresponds to the autophosphorylation segment around Tyr751 of the PDGF receptor B subunit, it serves as an inhibitor of receptor tyrosine kinase/src homology region 2 (SH2) interactions that mediate mitogenic signal transduction pathways.