| CAS | 158778-21-3 |
| Sequence | Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu) |
| Sequence Single | Cyclo(-G(p)YVPML) |
| Molecular Formula | C32H49N6O10PS |
| Molecular Weight | 740.82 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Protein-Tyrosine Kinases |
| Description | Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu) corresponds to the autophosphorylation segment around Tyr751 of the PDGF receptor B subunit, it serves as an inhibitor of receptor tyrosine kinase/src homology region 2 (SH2) interactions that mediate mitogenic signal transduction pathways. |