| CAS | 1566528-51-5 |
| Sequence | Fluorescein-5-carbonyl-Lys-Lys-Ile-Ser-Gly-Arg-Leu-Ser-Pro-Ile-Met-Thr-Glu-Gln-NH2 |
| Sequence Single | Fluorescein-5-carbonyl-KKISGRLSPIMTEQ-NH2 |
| Molecular Formula | C89H133N21O26S |
| Molecular Weight | 1945.23 |
| Synonyms | 5-FAM-Forkhead-derived Peptide, Woodtide, FAM-labeled, Forkhead derived peptide |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | 5-FAM-Woodtide also called 5-FAM-Forkhead-derived Peptide, Woodtide, FAM-labeled, Forkhead derived peptide, is a FAM-labeled Forkhead derived peptide woodtide (ab/em = 494/521 nm), it is used as a substrate for the DYRK family of kinases in in-vitro analysis. Woodtide corresponds to residues 324-334 of transcription factor FKHR with two lysine residues added at the N-terminus to facilitate binding to phosphocellulose paper. |
| References | 1. Topological isomers of human uroguanylin: interconversion between biologically active and inactive isomers. N.Chino et al., FEBS Lett., 421, 27 (1998) 2. The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase. Y.L.Woods et al., Biochem. J., 355, 609 (2001) 3. The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site. Y.L.Woods et al., Biochem. J., 355, 597 (2001) |