| CAS | 95751-30-7 |
| Sequence | Pyr-Phe-Thr-Asn-Val-Ser-Cys-Thr-Thr-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Gln-Arg-Leu-His-Asn-Thr-Ser-Arg-Gly-Lys-Cys-Met-Asn-Lys-Lys-Cys-Arg-Cys-Tyr-Ser-OH (Disulfide bonds between Cys7 and Cys28/Cys13 and Cys33/Cys17 and Cys35) |
| Sequence Single | pEFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS |
| Molecular Formula | C176H277N57O55S7 |
| Molecular Weight | 4295.95 |
| Synonyms | ChTX |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Ion Channel Modulating Agents |
| Description | Charybdotoxin also called ChTX, is a 37-amino acid peptide which has been found in the venom of the scorpion Leiurus quinquestriatus. It is a potent and selective inhibitor of the Ca2+ activated K+ channel present in GH3 anterior pituitary cells and primary bovine aortic smooth muscle cells. |
| References | 1. Charybdotoxin and its effects on potassium channels. M L Garcia , et al. Am J Physiol. 1995 Jul;269(1 Pt 1):C1-10. |