PeptideDB

Camstatin

CAS No.: 1002295-95-5

Camstatin, a functionally active 25-residue fragment of PEP-19’s IQ motif, binds calmodulin and inhibits neuronal nitri
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CAS 1002295-95-5
Sequence H-Ala-Pro-Glu-Thr-Glu-Arg-Ala-Ala-Val-Ala-Ile-Gln-Ala-Gln-Phe-Arg-Lys-Phe-Gln-Lys-Lys-Lys-Ala-Gly-Ser-NH2
Sequence Single APETERAAVAIQAQFRKFQKKKAGS-NH2
Molecular Formula C122H203N39O34
Molecular Weight 2760.19
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description Camstatin, a functionally active 25-residue fragment of PEP-19’s IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase.
References 1.  CamSTAT are peptide antagonists of calumodulin based upon a conserved structural motif in PEP-19, a neurogranin and neuromodulin. lemmon et al (1996). J.Biol.Chem. 271 15911 PMID: 8663125 2.  The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19. J Bradley Dickerson, et al. Brain Res. 2006 May 30;1092(1):16-27.