| CAS | 172617-89-9 |
| Sequence | Ac-Nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2 |
| Sequence Single | Ac-Nle-QHfRwG-NH2 |
| Molecular Formula | C47H65N15O9 |
| Molecular Weight | 984.13 |
| Synonyms | HP-228 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Nitric Oxide Research |
| Description | Acetyl-(Nle4,Gln5,D-Phe7,D-Trp9)-α-MSH (4-10) amide also called HP-228, is a potent protective agent against endotoxin shock. HP-228 prevented in vivo but not in vitro induction of nitric oxide synthase (NOS) by lipopolysaccharide (LPS). |