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Acetyl-(Nle4,Gln5,D-Phe7,D-Trp9)-α-MSH (4-10) amide

CAS No.: 172617-89-9

Acetyl-(Nle4,Gln5,D-Phe7,D-Trp9)-α-MSH (4-10) amide also called HP-228, is a potent protective agent against endotoxin
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CAS 172617-89-9
Sequence Ac-Nle-Gln-His-D-Phe-Arg-D-Trp-Gly-NH2
Sequence Single Ac-Nle-QHfRwG-NH2
Molecular Formula C47H65N15O9
Molecular Weight 984.13
Synonyms HP-228
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Nitric Oxide Research
Description Acetyl-(Nle4,Gln5,D-Phe7,D-Trp9)-α-MSH (4-10) amide also called HP-228, is a potent protective agent against endotoxin shock. HP-228 prevented in vivo but not in vitro induction of nitric oxide synthase (NOS) by lipopolysaccharide (LPS).