Acetyl-(Cys4,D-Phe7,Cys10)-α-MSH (4-13)

CAS No.: 91050-39-4

Acetyl-(Cys4,D-Phe7,Cys10)-α-MSH (4-13) also called [Ac-Cys4, DPhe7, Cys10] a-MSH (4-13), amide. The substitution of D-

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CAS	91050-39-4
Sequence	Ac-Cys-Glu-His-D-Phe-Arg-Trp-Cys-Lys-Pro-Val-NH2 (Disulfide bond)
Sequence Single	Ac-CEHfRWCKPV-NH2
Molecular Formula	C61H86N18O13S2
Molecular Weight	1343.6
Synonyms	[Ac-Cys4, DPhe7, Cys10] a-MSH (4-13), amide
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Pituitary & Hypothalamic Hormones
Description	Acetyl-(Cys4,D-Phe7,Cys10)-α-MSH (4-13) also called [Ac-Cys4, DPhe7, Cys10] a-MSH (4-13), amide. The substitution of D-Phe7 for L-Phe7 in this cyclic MSH sequence led to a superagonist with ultraprolonged melanotropic activity in the frog and lizard skin bioassays. Additionally, Acetyl-(Cys4,D-Phe7,Cys10)-α-MSH (4-13) showed a complete resistance to tryptic degradation.

Acetyl-(Nle4,Gln5,D-Phe7,D-Trp9)-α-MSH (4-10) amide

(Met5,Pro6,D-Phe7,D-Trp9,Phe10)-α-MSH (5-13)