CAS | 247062-33-5 |
Sequence | H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2 |
Sequence Single | AVSEHQLLHDKGKSIQDLRRRELLEKLL-Aib-KLHT-NH2 |
Molecular Formula | C174H300N56O49 |
Molecular Weight | 3960.64 |
Synonyms | BIM-44058, BA 058, (Aib29)-Semparatide |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Osteoporosis Research |
Description | Abaloparatide also called BIM-44058, BA 058, (Aib29)-Semparatide, is a pTHrP-analog promoting bone growth, it has been developed for the treatment of osteoporosis. |
References | 1. Vipericidins: a novel family of cathelicidin-related peptides from the venom gland of South American pit vipers. C.B.Falcao et al., Amino Acids, 46, 2561 (2014) 2. Effects of abaloparatide, a human parathyroid hormone-related peptide analog, on bone mineral density in postmenopausal women with osteoporosis. B.Z.Leder et al., J. Clin. Endocrinol. Metab., 100, 697 (2015) |