Tricosanoic acid is a long-chain fatty acid that has been shown to be an activator of hair growth.

Physicochemical Properties

Molecular Formula	C23H46O2
Molecular Weight	354.6101
Exact Mass	354.349
CAS #	2433-96-7
Related CAS #	93966-37-1 (lead salt);94087-10-2 (aluminum salt);98978-62-2 (calcium salt)
PubChem CID	17085
Appearance	White to off-white solid powder
Density	0.9±0.1 g/cm3
Boiling Point	399.0±5.0 °C at 760 mmHg
Melting Point	77-79 °C(lit.)
Flash Point	179.3±12.5 °C
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.459
LogP	10.87
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	21
Heavy Atom Count	25
Complexity	263
Defined Atom Stereocenter Count	0
InChi Key	XEZVDURJDFGERA-UHFFFAOYSA-N
InChi Code	InChI=1S/C23H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23(24)25/h2-22H2,1H3,(H,24,25)
Chemical Name	tricosanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. ARYL SULFONOHYDRAZIDES. EP0129778.

Additional Infomation

Tricosanoic acid is a very long-chain fatty acid that is tricosane in which one of the methyl groups has been oxidised to the corresponding carboxylic acid. It has a role as a plant metabolite, a human metabolite and a Daphnia magna metabolite. It is a straight-chain saturated fatty acid and a very long-chain fatty acid. It is a conjugate acid of a tricosanoate. Tricosanoic acid has been reported in Loranthus tanakae, Saussurea medusa, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

Ethanol : ~5 mg/mL (~14.10 mM)

Solubility (In Vivo)

Solubility in Formulation 1: 0.5 mg/mL (1.41 mM) in 10% EtOH + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), suspension solution; with sonication. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 5.0 mg/mL clear EtOH stock solution to 400 μL of PEG300 and mix evenly; then add 50 μL of Tween-80 to the above solution and mix evenly; then add 450 μL of normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 0.5 mg/mL (1.41 mM) (saturation unknown) in 10% EtOH + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 5.0 mg/mL clear EtOH stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.8200 mL	14.1000 mL	28.2000 mL
	5 mM	0.5640 mL	2.8200 mL	5.6400 mL
	10 mM	0.2820 mL	1.4100 mL	2.8200 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.