TS-002455 (Example 668) is an inhibitor of Lin28a-dep Z11 with IC50 < 1 μM. TS-002455 is the enantiomer of TS-002266.

Physicochemical Properties

Molecular Formula	C31H32CL2N6O5
Molecular Weight	639.53
CAS #	2702331-04-0
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Compounds targeting rna-binding proteins or rna-modifying proteins. WO2021178420.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.5636 mL	7.8182 mL	15.6365 mL
	5 mM	0.3127 mL	1.5636 mL	3.1273 mL
	10 mM	0.1564 mL	0.7818 mL	1.5636 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.