(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol (Adenosine, 3'-O-methyl- (8CI)(9CI)) is an adenosine nucleoside analog. Adenosine analogs are mostly used as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Popular products in this series include Adenosine phosphate, Acadesine, Clofarabine, Fludarabine phosphate and Vidarabine.

Physicochemical Properties

Molecular Formula	C11H15N5O4
Molecular Weight	281.27
CAS #	10300-22-8
Appearance	White to off-white solid powder
SMILES	OCC1OC(N2C=NC3C(=NC=NC2=3)N)C(O)C1OC
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~355.53 mM; with ultrasonication)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.5553 mL	17.7765 mL	35.5530 mL
	5 mM	0.7111 mL	3.5553 mL	7.1106 mL
	10 mM	0.3555 mL	1.7777 mL	3.5553 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.