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Remdesivir methylpropyl ester analog 3047145-80-9

Remdesivir methylpropyl ester analog 3047145-80-9

CAS No.: 3047145-80-9

Remdesivir methylpropyl ester analog (GS-5734 methylpropyl ester analog) is a derivative of Remdesivir. Remdesivir (GS-5
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Remdesivir methylpropyl ester analog (GS-5734 methylpropyl ester analog) is a derivative of Remdesivir. Remdesivir (GS-5734) is a nucleoside analog with antiviral activity.

Physicochemical Properties


Molecular Formula C25H31N6O8P
Molecular Weight 574.52
CAS # 3047145-80-9
Synonyms

GS-5734 methylpropyl ester analog
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


References

[1]. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.


Solubility Data


Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 1.7406 mL 8.7029 mL 17.4058 mL
5 mM 0.3481 mL 1.7406 mL 3.4812 mL
10 mM 0.1741 mL 0.8703 mL 1.7406 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.