Mal-C5-Gly-Gly-Phe-MMAE (Compound S5) is a drug-linker conjugate for ADC. Mal-C5-Gly-Gly-Phe-MMAE is composed of MMAE and linker. Mal-C5-Gly-Gly-Phe-MMAE can be used for the synthesis of ADC and cancer research.

Physicochemical Properties

Molecular Formula	C68H104N10O14
Molecular Weight	1285.61
CAS #	3056230-14-6
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. LINKER AND DRUG CONJUGATE USING SAME, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF. WO2024188314. 2024 September 19.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.7778 mL	3.8892 mL	7.7784 mL
	5 mM	0.1556 mL	0.7778 mL	1.5557 mL
	10 mM	0.0778 mL	0.3889 mL	0.7778 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.