RSRGVFF (FOXP3 inhibitor P60) is a mixed angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, with an IC50 value of 5.01 μM. RSRGVFF can bind to ACE and its substrate HHL complex at the active site and inactive site, thereby reducing the catalytic activity of ACE. RSRGVFF can be further used in the study of lowering hypertension.

Physicochemical Properties

Molecular Formula	C40H61N13O9
Molecular Weight	867.99
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	IC50: 5.01 μM (ACE)[1].
References	[1]. Screening, ACE-inhibitory mechanism and structure-activity relationship of a novel ACE-inhibitory peptide from Lepidium meyenii (Maca) protein hydrolysateJ. Food Bioscience, 2023, 52: 102374.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.1521 mL	5.7604 mL	11.5209 mL
	5 mM	0.2304 mL	1.1521 mL	2.3042 mL
	10 mM	0.1152 mL	0.5760 mL	1.1521 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.