O-Desmethyl Mebeverine alcohol HCl is a metabolite of Mebeverine, a potent α1 receptor (α1 receptor) inhibitor used as an antispasmodic drug in the digestive tract.

Physicochemical Properties

Molecular Formula	C15H26CLNO2
Molecular Weight	287.825443744659
Exact Mass	287.165
CAS #	856620-39-8
Related CAS #	Mebeverine-d6 hydrochloride;1329647-20-2;O-Desmethyl Mebeverine alcohol;155172-67-1
PubChem CID	129012195
Appearance	White to off-white solid powder
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	8
Heavy Atom Count	19
Complexity	203
Defined Atom Stereocenter Count	0
InChi Key	BWCVTLCWTXRTLL-UHFFFAOYSA-N
InChi Code	InChI=1S/C15H25NO2.ClH/c1-3-16(10-4-5-11-17)13(2)12-14-6-8-15(18)9-7-14;/h6-9,13,17-18H,3-5,10-12H2,1-2H3;1H
Chemical Name	4-[2-[ethyl(4-hydroxybutyl)amino]propyl]phenol;hydrochloride
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets

α1 repector

Solubility Data

Solubility (In Vitro)	H2O: ≥ 75 mg/mL (260.57 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (347.43 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.4743 mL	17.3714 mL	34.7427 mL
	5 mM	0.6949 mL	3.4743 mL	6.9485 mL
	10 mM	0.3474 mL	1.7371 mL	3.4743 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.