LU9 is a potent 3CLpro inhibitor with an IC50 value of 0.34 µM. LU9 has the potential to be used in SARS-CoV-2 research.

Physicochemical Properties

Molecular Formula	C22H29CL2N9O4
Molecular Weight	554.43
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	IC50: 0.34 µM (3CLpro)[1]
References	[1]. Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors. J Am Chem Soc. 2024 Dec 11;146(49):33983-33996.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.8037 mL	9.0183 mL	18.0365 mL
	5 mM	0.3607 mL	1.8037 mL	3.6073 mL
	10 mM	0.1804 mL	0.9018 mL	1.8037 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.