L-Gulose is the furanose form of L-sorbosone, an L-hexose sugar, and a biological intermediate for the synthesis of vitamin C.

Physicochemical Properties

Molecular Formula	C6H12O6
Molecular Weight	180.16
Exact Mass	180.063
CAS #	6027-89-0
PubChem CID	80127
Appearance	Off-white to light yellow solid powder
Density	1.7±0.1 g/cm3
Boiling Point	410.8±45.0 °C at 760 mmHg
Melting Point	132ºC
Flash Point	202.2±28.7 °C
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.635
LogP	-1.88
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Heavy Atom Count	12
Complexity	138
Defined Atom Stereocenter Count	4
SMILES	C([C@@H]([C@H]([C@@H]([C@@H](C=O)O)O)O)O)O
InChi Key	GZCGUPFRVQAUEE-JGWLITMVSA-N
InChi Code	InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5-,6-/m1/s1
Chemical Name	(2S,3S,4R,5S)-2,3,4,5,6-pentahydroxyhexanal
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Targets	Microbial Metabolite Human Endogenous Metabolite
References	[1]. Microbial production of L-ascorbic acid from D-sorbitol, L-sorbose, L-gulose, and L-sorbosone by Ketogulonicigenium vulgare DSM 4025. Biosci Biotechnol Biochem. 2005 Mar;69(3):659-62.
Additional Infomation	Aldehydo-L-gulose is a L-gulose and an aldehydo-gulose. It is an enantiomer of an aldehydo-D-gulose.

Solubility Data

Solubility (In Vitro)	H2O: 250 mg/mL (1387.66 mM)
Solubility (In Vivo)	Solubility in Formulation 1: 100 mg/mL (555.06 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.5506 mL	27.7531 mL	55.5062 mL
	5 mM	1.1101 mL	5.5506 mL	11.1012 mL
	10 mM	0.5551 mL	2.7753 mL	5.5506 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.