Physicochemical Properties
| Molecular Formula | C₄H₈O₃ |
| Molecular Weight | 104.10 |
| Exact Mass | 104.047 |
| CAS # | 627-03-2 |
| PubChem CID | 12301 |
| Appearance | Colorless to light yellow liquid |
| Density | 1.102 g/mL at 25 °C(lit.) |
| Boiling Point | 97-100 °C11 mm Hg(lit.) |
| Flash Point | 208 °F |
| Index of Refraction | n20/D 1.419(lit.) |
| LogP | 0.107 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Heavy Atom Count | 7 |
| Complexity | 60 |
| Defined Atom Stereocenter Count | 0 |
| SMILES | O(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])[H] |
| InChi Key | YZGQDNOIGFBYKF-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C4H8O3/c1-2-7-3-4(5)6/h2-3H2,1H3,(H,5,6) |
| Chemical Name | 2-ethoxyacetic acid |
| Synonyms | Ethoxyacetic acid; Ethoxyacetic acid |
| HS Tariff Code | 2934.99.9001 |
| Storage |
Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition | Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs) |
Biological Activity
| Additional Infomation |
Ethoxyacetic acid is a liquid. (NTP, 1992) Ethoxyacetic acid is a carboxylic acid. Ethoxyacetic acid has been reported in Montipora with data available. |
Solubility Data
| Solubility (In Vitro) | DMSO : ~75 mg/mL (~720.46 mM) |
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 3.75 mg/mL (36.02 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 37.5 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 3.75 mg/mL (36.02 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 37.5 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 3.75 mg/mL (36.02 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 37.5 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 9.6061 mL | 48.0307 mL | 96.0615 mL | |
| 5 mM | 1.9212 mL | 9.6061 mL | 19.2123 mL | |
| 10 mM | 0.9606 mL | 4.8031 mL | 9.6061 mL |