Physicochemical Properties
| Molecular Formula | C15H11O |
| Molecular Weight | 207.24724 |
| Exact Mass | 207.08 |
| CAS # | 11029-12-2 |
| PubChem CID | 145858 |
| Appearance | Brown to reddish brown solid powder |
| LogP | 4.38 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 1 |
| Heavy Atom Count | 16 |
| Complexity | 220 |
| Defined Atom Stereocenter Count | 0 |
| InChi Key | NWKFECICNXDNOQ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C15H11O/c1-2-6-12(7-3-1)15-11-10-13-8-4-5-9-14(13)16-15/h1-11H/q+1 |
| Chemical Name | 2-phenylchromenylium |
| HS Tariff Code | 2934.99.9001 |
| Storage |
Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition | Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs) |
Biological Activity
| ln Vitro | Leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase, and esterase activities were all affected by enocyanin (0.1%) to varying degrees, with results of 63%, 100%, 134%, and 99%, respectively [1]. |
| References |
[1]. A study on the toxicity of natural food dyes--toxicity and enzyme inhibition in Paramecium caudatum. J Toxicol Sci. 1978 May;3(2):127-36. |
| Additional Infomation |
Flavylium is a member of the class of chromenyliums that is chromenylium with a phenyl substituent at position 2. It is functionally related to a chromenylium. Flavylium has been reported in Tradescantia pallida and Callistephus chinensis with data available. A group of FLAVONOIDS derived from FLAVONOLS, which lack the ketone oxygen at the 4-position. They are glycosylated versions of cyanidin, pelargonidin or delphinidin. The conjugated bonds result in blue, red, and purple colors in flowers of plants. See also: Anthocyanins, grape (annotation moved to). |
Solubility Data
| Solubility (In Vitro) | DMSO : ≥ 50 mg/mL H2O : ~5 mg/mL |
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (Infinity mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (Infinity mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: 1.5 mg/mL (Infinity mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with ultrasonication. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.8251 mL | 24.1255 mL | 48.2509 mL | |
| 5 mM | 0.9650 mL | 4.8251 mL | 9.6502 mL | |
| 10 mM | 0.4825 mL | 2.4125 mL | 4.8251 mL |