Arachidonyl alcohol is a long chain primary fatty alcohol. Arachidonyl alcohol can be used as a substrate for the production of ether lipids.

Physicochemical Properties

Molecular Formula	C20H34O
Molecular Weight	290.48336
Exact Mass	290.261
CAS #	13487-46-2
PubChem CID	10891603
Appearance	Typically exists as solid at room temperature
LogP	6.124
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	14
Heavy Atom Count	21
Complexity	297
Defined Atom Stereocenter Count	0
SMILES	OCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC
InChi Key	NYBCZSBDKXGAGM-DOFZRALJSA-N
InChi Code	InChI=1S/C20H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21/h6-7,9-10,12-13,15-16,21H,2-5,8,11,14,17-20H2,1H3/b7-6-,10-9-,13-12-,16-15-
Chemical Name	(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-ol
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	Wax esters are created when arachidonic alcohol, which can be produced from arachidonic acid, builds up inside of cells. An novel kind of Acinetobacter sp. Arachidonic acid can be effectively converted to arachidonic acid by N-476-2 [1].
References	[1]. Toshihiro Nagao, et al. Microbial Conversion of Arachidonic Acid to Arachidonyl Alcohol by a New Acinetobacter Species. Journal of the American Oil Chemists' Society volume 89, pages1663–1671(2012)
Additional Infomation	(5Z,8Z,11Z,14Z)-icosatetraen-1-ol is a long-chain primary fatty alcohol that is (5Z,8Z,11Z,14Z)-icosatetraene in which one of the methyl hydrogens at position 1 is replaced by a hydroxy group.

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~344.26 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.08 mg/mL (7.16 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.08 mg/mL (7.16 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.08 mg/mL (7.16 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.4426 mL	17.2129 mL	34.4258 mL
	5 mM	0.6885 mL	3.4426 mL	6.8852 mL
	10 mM	0.3443 mL	1.7213 mL	3.4426 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.