Physicochemical Properties
| CAS # | 2349295-23-2 |
| Related CAS # | DiZPK;1337883-32-5 |
| PubChem CID | 134694958 |
| Appearance | White to off-white solid powder |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 10 |
| Heavy Atom Count | 21 |
| Complexity | 366 |
| Defined Atom Stereocenter Count | 1 |
| HS Tariff Code | 2934.99.9001 |
| Storage |
Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition | Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs) |
Biological Activity
| ln Vitro | As a photocrosslinker for detecting direct protein-protein interactions in living prokaryotic and eukaryotic cells, DiZPK hydrochloride is a structural analog of pyrrolysine (Pyl)[1]. |
| References | [1]. Zhang M, et al. A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance. Nat Chem Biol. 2011 Sep 4;7(10):671-7. |
Solubility Data
| Solubility (In Vitro) |
H2O: 8.33 mg/mL (25.89 mM) DMSO: < 1 mg/mL |
| Solubility (In Vivo) |
Solubility in Formulation 1: 2 mg/mL (6.22 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication. (Please use freshly prepared in vivo formulations for optimal results.) |