Colterol hydrochloride is the hydrochloride form of Colterol. Colterol hydrochloride is an adrenergic receptor agonist with good affinity for β1-adrenoceptor (heart) and β2-adrenoceptor (lung) with IC50 of 645 nM and 147 nM, respectively. Colterol hydrochloride has the potential to act as a bronchodilator.

Physicochemical Properties

Molecular Formula	C12H20CLNO3
Molecular Weight	261.75
CAS #	52872-37-4
Related CAS #	Colterol;18866-78-9
SMILES	CC(C)(C)NCC(C1=CC(=C(C=C1)O)O)O.Cl
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Binding of a catechol derivative of denopamine (T-0509) and N-tert-butylnoradrenaline (Colterol) to beta 1- and beta 2-adrenoceptors. Biol Pharm Bull. 1994 Aug;17(8):1023-7. [2]. Bitolterol mesylate: a beta-adrenergic agent. Chemistry, pharmacokinetics, pharmacodynamics, adverse effects and clinical efficacy in asthma. Pharmacotherapy. 1985 May-Jun;5(3):127-37.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	3.8204 mL	19.1022 mL	38.2044 mL
	5 mM	0.7641 mL	3.8204 mL	7.6409 mL
	10 mM	0.3820 mL	1.9102 mL	3.8204 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.