Antitumor agent-191 (Compound 7) exhibits antiviral activity against HSV-1 and HIV with EC50 of 0.03 μM and 0.81 μM, respectively. Antitumor agent-191 exhibits potential antitumor activity and can inhibit cancer cells HepG2, WI-38, Vero and MCF-7 with IC50 of 19.6, 39.3, 18.3 and 28 μM, respectively.

Physicochemical Properties

Molecular Formula	C22H14N12S2
Molecular Weight	510.56
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Synthetic approaches for novel fused pyrimidine derivatives: Design, structural characterization, antiviral, antitumor, and molecular docking evaluation. Heliyon. 2024 Dec 4;10(24):e40903.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.9586 mL	9.7932 mL	19.5863 mL
	5 mM	0.3917 mL	1.9586 mL	3.9173 mL
	10 mM	0.1959 mL	0.9793 mL	1.9586 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.