Afimkibart (PF-06480605) is a human IgG1 monoclonal antibody targeting tumor necrosis factor-like ligand 1A (TL1A). Afimkibart can be used in the research of inflammatory bowel disease.

Physicochemical Properties

Related CAS #	Bradford Protein Assay Kit;Cell Counting Kit-8;Cell-ATP Viability Detection Kit;Protein A Agarose;HOLO Human Interleukin-2 (IL-2) Detection Kit
Appearance	Colorless to light yellow liquid
Synonyms	PF-06480605; RVT-3101
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Anti-TL1A antibody PF-06480605 safety and efficacy for ulcerative colitis: a phase 2a single-arm studyJ. Clinical Gastroenterology and Hepatology, 2021, 19(11): 2324-2332. e6.

Solubility Data