Discovered by a Japanese group, A 17002 C is a new metabolite produced by Actinoplanes strains, structurally related to the virginiamycin factor M. On the basis of physico-chemical data, MS, IR, 1H and 13C NMR, structure I is assigned to A 17002 C.

Physicochemical Properties

Molecular Formula	C26H37N3O6
Molecular Weight	487.58848
Exact Mass	487.268
CAS #	71843-98-6
Related CAS #	71843-98-6
PubChem CID	6443619
Appearance	Typically exists as solid at room temperature
LogP	3.155
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	1
Heavy Atom Count	35
Complexity	822
Defined Atom Stereocenter Count	4
SMILES	OC1CC2=NC(=CO2)C(=O)NC(C)C(=O)OC(C(C)C)C(C)C=CC(=O)NCC=CC(C)=CCC1 |c:32,t:23,29|
InChi Key	HYYZDUUXSSRJQZ-YIBNVXJJSA-N
InChi Code	InChI=1S/C26H37N3O6/c1-16(2)24-18(4)11-12-22(31)27-13-7-9-17(3)8-6-10-20(30)14-23-29-21(15-34-23)25(32)28-19(5)26(33)35-24/h7-9,11-12,15-16,18-20,24,30H,6,10,13-14H2,1-5H3,(H,27,31)(H,28,32)/b9-7-,12-11-,17-8-/t18-,19-,20+,24-/m1/s1
Chemical Name	(4R,7R,8R,9Z,14Z,16Z,20S)-20-hydroxy-4,8,16-trimethyl-7-propan-2-yl-6,23-dioxa-3,12,25-triazabicyclo[20.2.1]pentacosa-1(24),9,14,16,22(25)-pentaene-2,5,11-trione
Synonyms	A17002C; A-17002 C;A17002 C; A-17002C; A 17002 C; A 17002C
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	In vitro activity: Kinase Assay: Cell Assay:
ln Vivo
Animal Protocol
References	J Antibiot (Tokyo).1979 Feb;32(2):108-14.

Solubility Data

Solubility (In Vitro)	DMSO: Water: Ethanol:
Solubility (In Vivo)	(Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	2.0509 mL	10.2545 mL	20.5090 mL
	5 mM	0.4102 mL	2.0509 mL	4.1018 mL
	10 mM	0.2051 mL	1.0255 mL	2.0509 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.