4-Fluorophenoxyacetic acid (4FPA) induces parthenocarpy. 4-Fluorophenoxyacetic acid (4FPA) protects grains from flukes thereby increasing field rice yields.

Physicochemical Properties

Molecular Formula	C8H7FO3
Molecular Weight	170.14
Exact Mass	170.037
CAS #	405-79-8
PubChem CID	67882
Appearance	White to off-white solid powder
Density	1.3±0.1 g/cm3
Boiling Point	295.2±15.0 °C at 760 mmHg
Melting Point	104-104.5 °C(lit.)
Flash Point	132.4±20.4 °C
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.520
LogP	1.47
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	12
Complexity	152
Defined Atom Stereocenter Count	0
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Control of Annual Bluegrass and Crabgrass in Turf with Fluorophenoxyacetic Acids. Weed Science. January 1958 , pp. 52-58. [2]. Induction of Defense in Cereals by 4-fluorophenoxyacetic Acid Suppresses Insect Pest Populations and Increases Crop Yields in the Field. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12017-12028.

Solubility Data

Solubility (In Vitro)

DMSO: 25 mg/mL (146.94 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (14.69 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (14.69 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (14.69 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.8775 mL	29.3876 mL	58.7751 mL
	5 mM	1.1755 mL	5.8775 mL	11.7550 mL
	10 mM	0.5878 mL	2.9388 mL	5.8775 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.