2,4-Difluorobenzaldehyde is an organic/chemical reagent that can be used as an intermediate for medicines, pesticides, and liquid crystal materials.

Physicochemical Properties

Molecular Formula	C7H4F2O
Molecular Weight	142.10
Exact Mass	142.023
CAS #	1550-35-2
PubChem CID	73770
Appearance	Typically exists as solid at room temperature
Density	1.3±0.1 g/cm3
Boiling Point	168.6±0.0 °C at 760 mmHg
Melting Point	2-3 °C(lit.)
Flash Point	55.0±0.0 °C
Vapour Pressure	1.6±0.3 mmHg at 25°C
Index of Refraction	1.514
LogP	1.69
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Heavy Atom Count	10
Complexity	127
Defined Atom Stereocenter Count	0
SMILES	FC1C=C(F)C=CC=1C=O
InChi Key	WCGPCBACLBHDCI-UHFFFAOYSA-N
InChi Code	InChI=1S/C7H4F2O/c8-6-2-1-5(4-10)7(9)3-6/h1-4H
Chemical Name	2,4-difluorobenzaldehyde
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. 2,4-Difluorobenzaldehyde is an organic chemical, that can be used in medicine, pesticide, liquid crystal materials intermediate.

Solubility Data

Solubility (In Vitro)

DMSO: 100 mg/mL (703.73 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (17.59 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (17.59 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (17.59 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	7.0373 mL	35.1865 mL	70.3730 mL
	5 mM	1.4075 mL	7.0373 mL	14.0746 mL
	10 mM	0.7037 mL	3.5186 mL	7.0373 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.