2,3,5-Trichloropyridine is a biochemical compound that may be utilized as a biomaterial or organic/chemical reagent for biomedical research.

Physicochemical Properties

Molecular Formula	C5H2CL3N
Molecular Weight	182.44
Exact Mass	180.925
CAS #	16063-70-0
PubChem CID	27666
Appearance	White to light brown solid powder
Density	1.5±0.1 g/cm3
Boiling Point	215.7±35.0 °C at 760 mmHg
Melting Point	46-50 °C(lit.)
Flash Point	104.7±11.5 °C
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.573
LogP	2.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Heavy Atom Count	9
Complexity	98.2
Defined Atom Stereocenter Count	0
SMILES	C1=C(C=NC(=C1Cl)Cl)Cl
InChi Key	CNLIIAKAAMFCJG-UHFFFAOYSA-N
InChi Code	InChI=1S/C5H2Cl3N/c6-3-1-4(7)5(8)9-2-3/h1-2H
Chemical Name	2,3,5-trichloropyridine
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Solubility Data

Solubility (In Vitro)

DMSO: 100 mg/mL (548.13 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (13.70 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (13.70 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.4813 mL	27.4063 mL	54.8125 mL
	5 mM	1.0963 mL	5.4813 mL	10.9625 mL
	10 mM	0.5481 mL	2.7406 mL	5.4813 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.