| Description | Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor (IC50: 26.3 nM).Xanthine oxidoreductase-IN-3 can be used in acute hyperuricemia studies. |
| In vivo | Xanthine oxidoreductase-IN-3（5 mg/kg；口服）在给药后3小时内能有效降低急性高尿酸血症小鼠的尿酸水平。[1] |
| Target activity | XOR:26.3 nM |
| molecular weight | 299.72 |
| Molecular formula | C14H10ClN5O |
| CAS | 651769-78-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (150.15 mM) |
| References | 1. Peng W, et al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2023;246:114947. |