| Description | BCL6-IN-10 (Compound WK499) is an inhibitor of BCL6, disrupting its interaction with the SMRT protein and promoting apoptosis, cell cycle arrest, and DNA damage. It effectively hampers the proliferation of various AML cell lines, with IC50 values of 0.91, 1.63, 1.026, 7.42, 0.87, and 0.85μM for OCI-AML3, THP1, MOLM13, HL60, KG1, and NB4 cells, respectively [1]. |
| molecular weight | 498.33 |
| Molecular formula | C21H20BrN7O3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |