| Description | cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM for mouse cGAS. By inhibiting the abnormal activation of cGAS linked to numerous immune-mediated inflammatory diseases, cGAS-IN-1 possesses potential anti-inflammatory properties [1]. |
| molecular weight | 377.35 |
| Molecular formula | C18H19NO8 |
| CAS | 858770-07-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |