| Description | VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probability and single-channel current amplitude. |
| In vitro | VU6036720 通过降低通道开放状态的可能性及单通道电流幅度来抑制 Kir4.1/5.1 活性（IC50=0.24 μM）。[1] |
| molecular weight | 436.93 |
| Molecular formula | C20H22ClFN4O2S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (102.99 mM), Sonication is recommended. |
| References | 1. McClenahan SJ, et al. VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. Mol Pharmacol. 2022;101(5):357-370. |