| Description | VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM). |
| Target activity | mGlu5:81 nM |
| molecular weight | 333.41 |
| Molecular formula | C16H19N3O3S |
| CAS | 1848252-81-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Felts AS, et al. Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5. Bioorg Med Chem Lett. 2019 Jan 1;29(1):47-50. |