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VU0155041

CAS No.: 1093757-42-6

VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at
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Description VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
Target activity mGlu4 (rat):693 nM(EC50), mGlu4 (human):798nM(EC50)
Synonyms UV0155041, VU-0155041
molecular weight 316.18
Molecular formula C14H15Cl2NO3
CAS 1093757-42-6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 31.6 mg/mL (100 mM)
References 1. Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74(5):1345-58.