VIP(6-28)(human, rat, porcine, bovine) acetate Bioactivity,Chemical Properties,Storage & Solubility Information Pathways-PeptideDB

Description	VIP(6-28)(human, rat, porcine, bovine) acetate is an antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) receptor on cAMP in the superior cervical ganglion (SCG).
In vitro	VIP(6-28)(human, rat, porcine, bovine) acetate（10、30或100 μM）通过分别降低52%、64%或81%来减少10 μM VIP刺激后cAMP水平的增加。在富含神经元和非神经元的分离培养细胞中，对VIP(6-28)(human, rat, porcine, bovine) acetate阻断VIP刺激下cAMP水平增加的能力获得了类似结果。在测试的任何浓度下，VIP(6-28)(human, rat, porcine, bovine) acetate本身不改变cAMP水平。与其通过64%降低VIP刺激下cAMP水平提升的能力相比，向培养基中添加30 μM VIP(6-28)(human, rat, porcine, bovine) acetate后，在用异丙肾上腺素或福斯可林（每种10 μM）刺激成年神经节后测得的cAMP水平并没有显著改变。
molecular weight	2876.34
Molecular formula	C128H211N37O36S
Storage	store at low temperature,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
References	1. Mohney RP, et al. Vasoactive intestinal peptide enhances its own expression in sympathetic neurons after injury. J Neurosci. 1998 Jul 15;18(14):5285-93.

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