| Description | UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases. |
| Target activity | PI4KIIIβ:11 nM (cell free) |
| molecular weight | 410.47 |
| Molecular formula | C20H26N8O2 |
| CAS | 1616413-96-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 70 mg/mL (170.54 mM), Sonication is recommended. |
| References | 1. Reuberson J, et al. Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo. J Med Chem. 2018 Aug 9;61(15):6705-6723. |