| Description | Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it useful for cancer research. |
| In vitro | Tubulin polymerization-IN-44在浓度为0.42 μM作用24至48小时的条件下,有效抑制SGC-7910细胞的增殖,其半数抑制浓度(IC50)为0.21 μM。 |
| In vivo | Tubulin Polymers-in-44(5-20 mg/kg,每隔一天)能有效抑制乳腺癌4T1细胞小鼠模型的肿瘤生长,同时并不引起小鼠体重下降。 |
| molecular weight | 436.31 |
| Molecular formula | C19H15Cl2N3O3S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |