| Description | PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM, enhanced in vitro microsomal stability (t 1/2 = 44.6 min), and excellent efficacy in restoring long-term potentiation, making it suitable for Alzheimer’s disease (AD) research [1]. |
| Target activity | PDE5:20 nM |
| molecular weight | 360.41 |
| Molecular formula | C21H20N4O2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |