| Description | Tris(benzyltriazolylmethyl)amine (TBTA) is a tertiary amine with three 1, 2, 3-triazole groups. It complexes with, and stabilizes, copper(I) to accelerate azide-alkyne cycloadditions, as used in click chemistry. |
| Synonyms | 三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺, TBTA |
| molecular weight | 530.63 |
| Molecular formula | C30H30N10 |
| CAS | 510758-28-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (103.65 mM) |
| References | 1. Hong V, et al. Electrochemically Protected Copper(I)-Catalyzed Azide-Alkyne Cycloaddition[J]. Chembiochem, 2008, 9(9):1481-1486. |
| Citations | 1. Cheng J, Liu Y, Yan J, et al. Fumarate suppresses B-cell activation and function through direct inactivation of LYN. Nature Chemical Biology. 2022: 1-9 2. Zhan Y, Chen Q, Song Y, et al. Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells. Cell Biology and Toxicology. 2022: 1-21 |