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Tris(benzyltriazolylmethyl)amine

CAS No.: 510758-28-8

Tris(benzyltriazolylmethyl)amine (TBTA) is a tertiary amine with three 1, 2, 3-triazole groups. It complexes with, and s
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Description Tris(benzyltriazolylmethyl)amine (TBTA) is a tertiary amine with three 1, 2, 3-triazole groups. It complexes with, and stabilizes, copper(I) to accelerate azide-alkyne cycloadditions, as used in click chemistry.
Synonyms 三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺, TBTA
molecular weight 530.63
Molecular formula C30H30N10
CAS 510758-28-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 55 mg/mL (103.65 mM)
References 1. Hong V, et al. Electrochemically Protected Copper(I)-Catalyzed Azide-Alkyne Cycloaddition[J]. Chembiochem, 2008, 9(9):1481-1486.
Citations 1. Cheng J, Liu Y, Yan J, et al. Fumarate suppresses B-cell activation and function through direct inactivation of LYN. Nature Chemical Biology. 2022: 1-9 2. Zhan Y, Chen Q, Song Y, et al. Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells. Cell Biology and Toxicology. 2022: 1-21