| Description | TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases. |
| In vitro | TMPD dihydrochloride 通过展示CYP C氧化酶活性的方式区分有机体，并能区别革兰氏阴性与阳性的致病与非致病细菌。TMPD二氯化物可作为一种比色指示剂[1]。 |
| molecular weight | 237.17 |
| Molecular formula | C10H18Cl2N2 |
| CAS | 637-01-4 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 95 mg/mL (400.56 mM), Sonication is recommended. DMSO: 13 mg/mL (54.81 mM), Sonication is recommended. |
| References | 1. S Kuss, et al. Electrochemical recognition and quantification of cytochrome c expression in Bacillus subtilis and aerobe/anaerobe Escherichia coli using N, N, N', N'-tetramethyl- para-phenylene-diamine (TMPD). Chem Sci. 2017 Nov 1;8(11):7682-7688. 2. Nenad Petrovic, et al. Using N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) to assay cyclooxygenase activity in vitro. Methods Mol Biol. 2010;594:129-40. 3. Franco A Rossato, et al. Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration. PLoS One. 2014 Jun 25;9(6):e101060. |