| Description | BI 6015 is an antagonist of HNF4α. HNF4α is a nuclear receptor that regulates gene expression in the intestine cells, liver cells, and pancreas-β cells. |
| Synonyms | 2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑 |
| molecular weight | 331.35 |
| Molecular formula | C15H13N3O4S |
| CAS | 93987-29-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (150.9 mM) |
| References | 1. Kiselyuk A, Lee SH, Farber-Katz S, et al. HNF4a Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter. Chem Biol, 2012, 19(7): 806-818 |
| Citations | 1. Zhao Y, Tang H, Xu J, et al.HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer.Evolutionary Bioinformatics.2024, 20: 11769343241249017. |