| Description | TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities. |
| Synonyms | TLR7/8 agonist-5d, 二盐酸TLR7/8 agonist 1 |
| molecular weight | 432.39 |
| Molecular formula | C22H27Cl2N5 |
| CAS | 1620278-72-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 70 mg/mL (161.89 mM) |
| References | 1. Shukla NM, et al. Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6384-6. 2. Beesu M, et al. Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity. J Med Chem. 2015 Oct 8;58(19):7833-49. |
TLR7/8 agonist 1 dihydrochloride
CAS No.: 1620278-72-9
TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activit
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