| Description | Tiracizine HCl, a new class I antiarrhythmic drug, was studied in patients with ischemic heart disease and shown to decrease myocardial contractile function. |
| Synonyms | AWD-19-166, AWD19166, Bonnecor, AWD 19 166, Tiracizine Hydrochloride |
| molecular weight | 403.9 |
| Molecular formula | C21H26ClN3O3 |
| CAS | 78816-67-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Galenko-Iaroshevskiĭ PA, Khankoeva AI, Uvarov AV, Bartashevich VV, Popov PB, Sirotenko DV, Boldin VB. [Correction of the cardiotoxic effect of the anti-arrhythmia agents with befol, sufan, and their combination]. Biull Eksp Biol Med. 1998 Jun;125(6):641-6. Russian. PubMed PMID: 9693756. 2. Oertel R, Richter K, Gramatté T, Kirch W. Determination of drugs in biological fluids by high-performance liquid chromatography with on-line sample processing. J Chromatogr A. 1998 Feb 27;797(1-2):203-9. PubMed PMID: 9542112. 3. Mishin IuI, Kliachkina IL, Ivashkin VT, Min'kova TI, Bannikova SD. [The anti-arrhythmia action of tiracizine in patients with ischemic heart disease and decreased myocardial contractile function]. Voen Med Zh. 1997 Jun;318(6):44-7. Russian. PubMed PMID: 9412062. 4. Galenko-Iaroshevskiĭ PA, Khankoeva AI, Uvarov AV, Reznikov AIu, Galygo DS, Bartashevich VV. [Comparative anti-arrhythmia activity of befol, lidocaine, and bonnecor]. Biull Eksp Biol Med. 1996 Dec;122(12):665-8. Russian. PubMed PMID: 9280469. |