| Description | Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster and more consistent inhibition on ADP-receptors. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). |
| Synonyms | Ticagrelor metabolite M5,, T437700, 替格瑞洛杂质H, AR-C133913XX |
| molecular weight | 370.43 |
| Molecular formula | C14H22N6O4S |
| CAS | 1251765-07-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (134.98 mM) |
| References | 1. Teng R, Oliver S, Hayes MA, Butler K. Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects. Drug Metab Dispos. 2010 Sep;38(9):1514-21. doi: 10.1124/dmd.110.032250. Epub 2010 Jun 15. PubMed PMID: 20551239. |