| Description | N6-(4-Hydroxybenzyl)adenosine (Para-topolin riboside) is a platelet aggregation inhibitor. |
| In vitro | 几种天然存在的N(6)取代腺苷衍生物(细胞因子核苷)已在体外研究中作为胶原蛋白诱导的血小板聚集的抑制剂,并展现出了其活性范围(IC50:6.77-141 μM)[1]。 |
| Synonyms | Para-topolin riboside, N6-羟苄腺苷 |
| molecular weight | 373.36 |
| Molecular formula | C17H19N5O5 |
| CAS | 110505-75-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: < 0.1 mg/mL (insoluble) DMSO: 100 mg/mL (267.84 mM) |
| References | 1. Vistoli G, et al. Naturally occurring N(6)-substituted adenosines (cytokinin ribosides) are in vitro inhibitors of platelet aggregation: an in silico evaluation of their interaction with the P2Y(12) receptor. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5652-5655. |