| Description | Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells |
| In vitro | Telekin在肝细胞癌细胞中激活线粒体介导的凋亡途径，可能值得作为治疗肝细胞癌的潜在药物进一步研究[1]。 |
| molecular weight | 248.32 |
| Molecular formula | C15H20O3 |
| CAS | 6752-90-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 27.5 mg/ml (110.74 mM) |
| References | 1. Zheng B , Wu L , Ma L , et al. Telekin induces apoptosis associated with the mitochondria-mediated pathway in human hepatocellular carcinoma cells[J]. Biological & Pharmaceutical Bulletin, 2013, 36(7):1118. 2. Li L , Zheng B B , Ma L S , et al. Telekin suppresses human hepatocellular carcinoma cells in vitro by inducing G2/M phase arrest via the p38 MAPK signaling pathway[J]. Acta Pharmacologica Sinica, 2014, 35(10):1311-1322. |