| Description | TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors). |
| Target activity | OX1:3 nM, OX2:0.2nM |
| Synonyms | DORA-1 |
| molecular weight | 470.59 |
| Molecular formula | C27H26N4O2S |
| CAS | 916141-36-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (106.25 mM) Ethanol: 100 mM |
| References | 1. Bergman JM, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1425-30. |